Home » Publications

Publications

Advertisements

since 1999

  1. Greive SJ, Fung HKH, Chechik M, Jenkins HT, Weitzel SE, Aguiar PM, Brentnall AS, Glousieau M, Gladyshev GV, Potts JR and Antson AA: DNA recognition for virus assembly through multiple sequence-independent interactions with a helix-turn-helix motif. Nucleic Acids Research, 2015, doi: 10.1093/nar/gkv1467.
  2. Byrne RT, Jenkins HT, Peters DT, Whelan F, Stowell J, Aziz N, Kasatsky P, Rodnina MV, Koonin EV, Konevega AL and Antson AA: Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc. Natl. Acad. Sci. USA, 2015, 112: 6033-6037.
  3. Warrander F, Faas L, Kovalevskiy O, Peters D, Coles M, Antson AA, Genever P and Isaacs HV: Lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development. Dev Dynamics, 2015, doi: 10.1002/dvdy.24358.
  4. Chaban Y, Stead JA, Ryzhenkova K, Whelan F, Lamber EP, Antson AA, Sanders C M and Orlova EV: Structural basis for DNA strand separation by a hexameric replicative helicase. Nucleic Acids Research, 2015, 40:2271-2283.
  5. Whelan F, Jenkins HT, Griffiths SC, Byrne RT, Dodson EJ and Antson AA: From bacterial to human dihydrouridine synthase: automated structure determination. Acta Cryst D, 2015, 71: 1564-1571.
  6. Moor NA, Vasil’eva IA, Anarbaev RO, Antson AA and Lavrik OI: Quantitative characterization of protein-protein complexes involved in base excision DNA repair. Nucleic Acids Research, 2015, 43:6009-22.
  7. Williams LS, Levdikov VM, Minakhin L, Severinov K, Antson AA 12-Fold symmetry of the putative portal protein from the Thermus thermophilus bacteriophage G20C determined by X-ray analysis. Acta Cryst F, 2013, 69:1239-1241.
  8. Loredo-Varela J, Chechik M, Levdikov VM, Abd-El-Aziz A, Minakhin L, Severinov K, Smits C, Antson AA The putative small terminase from the thermophilic dsDNA bacteriophage G20C is a nine-subunit oligomer. Acta Cryst F, 2013, 69:876-879.
  9. Byrne RT, Whelan F, Aller P, Bird LE, Dowle A, Lobley CMC, Reddivari Y, Nettleship JE, Owens RJ, Antson AA and Waterman DG: S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA. Acta Cryst D, 2013, 69:1090-1098.
  10. Sluchanko NN, Artemova NV, Sudnitsyna MV, Safenkova IV, Antson AA, Levitsky DI, Gusev NB: Monomeric 14-3-3ζ Has a Chaperone-Like Activity and Is Stabilized by Phosphorylated HspB6. Biochemistry, 2012, 51:6127-3618.
  11. Büttner C, Chechik M, Ortiz-Lombardíaa M, Smits M, Ebong I-O, Chechik V, Jeschke G, Dykeman E, Benini S, Robinson CV, Alonso JC, Antson AA: Structural basis for DNA recognition and loading into a viral packaging motor. Proc. Natl. Acad. Sci. USA, 2012, 109:811-816.
  12. Luan W, Fesseler J, Chechik M, Buttner CR, Antson AA, Smits C: Recombinant portal protein from Staphylococcus epidermidis bacteriophage CNPH82 is a 13-subunit oligomer. Acta Cryst F, 2012, 68:1267-1270.
  13. Bayfield OW, Chen C-S, Patterson AR, Luan W, Smits C, Gollnick P, Antson AA: Trp RNA-binding attenuation protein: modifying symmetry and stability of a circular oligomer. PLoS ONE, 2012, e44309. doi:10.1371/journal.pone.0044309.
  14. Griffiths S, Byrne RT, Antson AA, Whelan F: Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase. Acta Cryst F, 2012, 68: 333-336.
  15. Whelan F, Stead J, Shkumatov AV, Svergun DI, Sanders C, Antson AA: A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding. Nucleic Acids Research 2012, 40:2271-2283.
  16. Milic D, Demidkina TV, Faleev NG, Phillips RS, Matkovic-Calogovic D and Antson AA: Crystallographic snapshots of tyrosine phenol-lyase show that substrate strain plays a role in C-C bond cleavage. J. Am. Chem. Soc. 2011, 133:16468-16476.
  17. Chen C-S, Smits C, Dodson GG, Shevtsov MB, Merlino N, Gollnick P and Antson AA: How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism. PLoS One 2011, 6: 1-11.
  18. Sluchanko N, Sudnitsyna MV, Seit-Nebi AS, Antson AA and Gusev NB: Properties of the monomeric form of human 14-3-3ζ protein and its interaction with tau and HspB6. Biochemistry 2011, 50:9797-808.
  19. Silva APG, Chechik M, Byrne RT, Waterman DG, Ng CL, Dodson EJ, Koonin EV, Antson AA, Smits C: Structure and Activity of a Novel Archaeal beta-CASP Protein with N-Terminal KH Domains. Structure  2011, 19: 622-632.
  20. Byrne RT, Konevega AL, Rodnina MV and Antson AA: The crystal structure of unmodified tRNAphe from Escherichia coli. Nucleic Acids Research, 2010, 38:4154-4162.
  21. Kovalevskiy OV, Solonin AS, Antson AA: Structural investigation of transcriptional regulator HlyIIR: Influence of a disordered region on protein fold and dimerization. Proteins, 2010, 78:1870-1877.
  22. Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M, The structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring. Acta Cryst D, 2010, 66:522-528.
  23. Shevtsov MB, Chen Y, Isupov MN, Leech A, Gollnick P, Antson AA. Bacillus licheniformis Anti-TRAP can assemble into two types of dodecameric particles with the same symmetry but inverted orientation of trimers. J Struct Biol., 2010, 170:127-133.
  24. Demidkina TV, Antson AA, Faleev NG, Phillips RS, Zakomirdina LN: Spatial structure and the mechanism of tyrosine phenol-lyase and tryptophan indole-lyase. Mol. Biol., 2009, 43:269-283.
  25. Smits C, Chechik M, Kovalevskiy OV,  Shevtsov MB, Foster AW, Alonso JC and Antson AA: Structural basis for the nuclease activity of a Bacteriophage Large Terminase. EMBO Reports, 2009, 10:592-598.
  26. Ng CL, Waterman DG, Koonin EV, Walters AD, Chong JPJ, Isupov MN, Lebedev AA, Bunka DHJ, Stockley PG, Ortiz-Lombardía M, Antson AA: Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein. BMC Struct. Biol., 2009, 9:32.
  27. Kovalevskiy OV, Antson AA, Solonin AS: Contraction of the disordered loop located within C-terminal domain of the transcriptional regulator HlyIIR causes its structural rearrangement. Mol. Biol., 2009, 43:114-122.
  28. Milic D, Demidkina TV, Faleev NG, Matkovic-Calogovic D and Antson AA:  Insights into the catalytic mechanism of tyrosine phenol-lyase from crystal structures of quinonoid intermediates. J Biol Chem., 2008, 283:29206-29214.
  29. Byrne RT, Waterman DG, Antson AA. Enzyme-substrate recognition in RNA-modifying enzymes. in DNA and RNA modification Enzymes : Comparative Structure, Mechanism, Functions, Cellular Interactions and Evolution. Edited by Henri Grosjean, 2009 LANDES Biosciences.
  30. Hernandez-Ramon EE, Burns JE, Zhang W, Walker HF, Allen S, Antson AA, Maitland NJ: Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region. J Virol 2008 82:4853-61.
  31. Silva APG, Byrne RT, Chechik M, Smits C, Waterman DG, Antson AA: Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus. Acta Cryst, 2008, F-64: 1083-1086.
  32. Hernandez-Ramon EE, Burns JE, Zhang W, Walker HF, Allen S, Antson AA, Maitland NJ: Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region. J Virol, 2008 82:4853-61.
  33. Lebedev A, Krause MH, Isidro AL, Vagin A, Orlova EV, Turner J, Dodson EJ, Tavares P, Antson AA: Structural framework for DNA translocation via the viral portal protein. EMBO J, 2007, 26:1984-94.
  34. Sanders CM, Kovalevskiy OV, Sizov D, Lebedev AA, Isupov MN, Antson AA Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors. Nucleic Acids Research, 2007, 35: 6451–6457.
  35. Cuervo A, Vaney MC, Antson AA, Tavares P, Oliveira L Structural rearrangements between portal protein subunits are essential  for viral DNA translocation. J Biol Chem,  2007, 282: 18907-18913.
  36. Sanders CM, Burgin D, Sizov D, Seavers PP, Ortiz-Lombardía M, Antson AA: Transcription activator structure reveals redox control of a replication initiation  reaction. Nucleic Acids Research, 2007, 35:3504-3515.
  37. Kovalevskiy OV, Lebedev AA, Surin AK, Solonin AS and Antson AA Crystal structure of Bacillus cereus HlyIIR, the transcriptional regulator of gene for pore-forming toxin Hemolysin II. J Mol Biol, 2007, 365: 825-834.
  38. Milic D, Matkovic-Calogovic D, Demidkina TV, Kulikova VV, Sinitzina NI, Antson AA:  Structures of apo and holo tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions. Biochemistry, 2006, 45: 7544-7552.
  39. Waterman, D.G., Ortiz-Lombardia M, Fogg MJ, Koonin EV and Antson AA:  Crystal Structure of Bacillus anthracis ThiI, a tRNA-modifying Enzyme Containing the Predicted RNA-binding THUMP Domain. J Mol Biol, 2006, 356: 97-110.
  40. Shevtsov MB, Chen Y, Gollnick P and Antson AA: Crystal structure of Bacillus subtilis anti-TRAP protein, an antagonist of TRAP/RNA interaction. Proc. Natl. Acad. Sci. U. S. A., 2005, 102: 17600-17605.
  41. Gollnick P, Babitzke P, Antson A, Yanofsky C: Complexity in regulation of tryptophan biosynthesis in Bacillus subtilis. Ann. Rev. Genet. 2005, 39: 47-68.
  42. Lebedev AA, Krause MH, Vagin A, Orlova EV, Dodson EJ, Tavares P, Antson AA: Crystal structure of the portal protein from bacteriophage SPP1 and model for DNA translocation. FEBS J, 2005, 272: 334.
  43. Gollnick P & Antson A: Going for RNA repeats. Nature Structural & Molecular Biology (2005) 12: 289 – 290.
  44. Ng CL, Waterman D, Koonin EV, Antson AA & Ortiz-Lombardia M: The crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases. EMBO reports (2005) 6:140-146.
  45. Levdikov VM, Blagova EV, Brannigan JA, Cladiere L, Antson AA, Isupov MN, Seror SJ, Wilkinson AJ: The crystal structure of YloQ, a circularly permuted GTPase essential for Bacillus subtilis viability. J. Mol. Biol. (2004) 340: 767-782.
    Shevtsov MB, Chen YL, Gollnick P & Antson AA: Anti-TRAP protein from Bacillus subtilis: crystallization and internal symmetry. Acta Cryst (2004) D60: 1311-1314.
    Hopcroft NH, Wendt AL, Brzozowski A, Gollnick P, & Antson AA: TRAP-RNA interactions during transcription regulation: the role of spacers and trinucleotide repeats. J. Mol. Biol. (2004) 338:43-53.
  46. Moroz OV, Antson AA, Grist SJ, Maitland NJ, Dodson GG, Wilson KS, Lukanidin E, Bronstein IB: Structure of the human S100A12-copper complex: implications for host-parasite defence. Acta Cryst (2003) D59:859-867.
  47. Murshudov GN, Grebenko AI, Brannigan JA, Antson AA, Barynin VV, Dodson GG, Dauter Z, Wilson KS, Melik-Adamyan WR: The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex. Acta Cryst (2002) D58: 1972-1982.
  48. Hopcroft NH, Wendt AL, Gollnick P & Antson AA: Specificity of TRAP-RNA interactions: crystal structures of two complexes with different RNA sequences. Acta Cryst (2002) D58:615-621.
  49. Moroz OV, Antson AA, Dodson EJ, Burrell HJ, Grist SJ, Lloyd RM, Maitland NJ, Dodson GG, Wilson KS, Lukanidin E & Bronstein IB: The structure of S100A12 in a hexameric form and its proposed role in receptor signalling. Acta Cryst (2002) D58: 407-413.
  50. Antson AA, Smith DJ, Roper DI, Lewis S, Caves LSD, Verma CS, Buckley SL, Lillford PJ & Hubbard RE: Understanding the mechanism of ice binding by type III antifreeze proteins. J.Mol.Biol. (2001) 305(4):875-889.
  51. Moroz OV, Antson AA, Murshudov GN, Maitland NJ, Dodson GG, Wilson KS, Skibshoj I, Lukanidin EM & Bronshtein IB: The three-dimensional structure of human S100A12. Acta Cryst. (2001) D57:20-29.
  52. Antson AA, Burns JE, Moroz OV, Scott DJ, Sanders CM, Bronstein IB, Dodson GG, Wilson KS, Maitland NJ: Structure of the intact transactivation domain of the human papillomavirus E2 protein. (2000) Nature, 403: 805-809.
  53. Antson AA: Single stranded RNA-binding proteins. (2000) Current Opinion in Structural Biology 10, 87-94.
  54. Moroz OV, Antson AA, Dodson GG, Wilson KS, Skibshoj I, Lukanidin EM, Bronstein IB: Crystallization and preliminary X-ray diffraction analysis of human calcium-binding protein S100A12. (2000) Acta Cryst. D- 56, 1819-191.
  55. Antson AA, Dodson EJ, Dodson G, Greaves RB, Chen, X-P & Gollnick P: Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA. (1999) Nature 401, 235-242.
  56. Chen XP, Antson AA, Li MYP, Baumann C, Dodson EJ, Dodson GG & Gollnick P: Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. (1999) J. Mol. Biol. 289, 1003-1016.
  57. BernierVillamor V, Camacho A, GonzalezPacanowska D, CedergrenZeppezauer E, Antson A, Wilson KS: Crystallization and preliminary X-ray diffraction of Trypanosoma cruzi dUTPase. (1999) Acta Cryst. D- 55, 528-530
  58. Lamers MBAC, Antson AA, Hubbard RE, Scott RK & Williams DH: Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine. (1999) J. Mol. Biol. 285, 713-725.

Recent publications

This slideshow requires JavaScript.

Advertisements