I am interested in the mechanisms of self-assembly and packaging of viral capsids and bacterial capsid-like species (encapsulins), using a combined structural approach consisting of cryo-electron microscopy and X-ray crystallography to study these species.
I graduated with an MChem (Hons) degree in Chemistry at the University of York in 2014, where my thesis work focussed on the purification and X-ray crystallography of phage proteins important in their life cycle. Whilst at the University of York I also spent time in the research facilities of Professor Simon Duckett (Centre for Hyperpolarization in Magnetic Resonance, York), where I worked on the optimisation of a system for para-Hydrogen induced hyperpolarisation in NMR which dramatically improves signal intensity. Throughout my undergraduate degree I published two papers and presented at two international conferences (GRC, FASEB). I now study for my PhD which is joint funded by the Wellcome Trust (UK) and NIH (US), where my time is divided between York and the NIH.
- Four Year PhD Studentship from Wellcome Trust and National Institutes of Health (2014)
- First Class Hons with distinction (2014)
- Margaret Bishop prize for best MChem project thesis and viva (2014)
- EPSRC vacation research scholarship (2011)
- Chemistry department vacation award (2011)
hao-Sheng Chen, Andrea R. Patterson, Weisha Luan, Callum Smits, Paul Gollnick, Alfred A. Antson, Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer, PLoS ONE, 2012, 7 (9), e44309. DOI: 10.1371/journal.pone.0044309
Marianna Fekete , Oliver W. Bayfield , Simon B. Duckett, Sam Hart , Ryan E. Mewis , Natalie Pridmore ,Peter J. Rayner , Adrian Whitwood, Iridium(III) hydrido N-heterocyclic carbene-phosphine complexes as catalysts in magnetization transfer reactions. Inorganic Chemistry, 2013, 52 (23), pp 13453–13461. DOI: 10.1021/ic401783c