Professor, Group leader
+44 (0)1904 328255
I graduated from the Moscow Institute of Physics and Technology (1986) and studied for a PhD at the Institute of Crystallography (Moscow, USSR Academy of Sciences) in the laboratory of protein structure led by Boris Vainstein. During 1987-1989, as a member of a working group, I was involved in the USSR Academy of Sciences initiative to set up a synchrotron radiation station for protein crystallography at the Institute of Nuclear Physics (Novosibirsk, Russia). After a number of visits to European Molecular Biology Laboratory in Hamburg (1990-1992) where I worked with Keith Wilson, in 1992 I joined the laboratory of Guy Dodson at York (now York Structural Biology Laboratory). Since 1998 my research has been supported by the Wellcome Trust, and this enabled me to set up a research group focused on studying the structures and mechanisms of several protein-nucleic acid assemblies.
- 1998 – 2002: Wellcome Trust Research Career Development Fellowship (4 years)
- 1992 – present: Research Fellow at York Structural Biology Laboratory, University of York (22 years)
- 2002 – present: Wellcome Trust Senior Research Fellowship (12 years)
Research in our group
Our group’s interests are in understanding the molecular events that control biological mechanisms, and we are concentrating on protein-nucleic acid interactions because of their key role in many biological processes important to human health. Our major aim is to study the structure and function of protein-nucleic acid complexes present in molecular motors by X-ray structural analysis combined with several biophysical and biochemical methods.